The Minipro TL866 is very popular among hobbyist because of its low price and ease of use. Its list of supported chips is however somewhat limited compared to more expensive professional programmers. The E2R16 adapter adds support for the ROM pinout compatible EPROM of the 27C400 series which are compatible with Amiga computers and many arcade machines.
The schematics is trivial. All it is necessary is to remap the 27C4096 pins to the corresponding 27C400 pins. C1 is a decoupling capacitor. R1 and R2 allow the adapter to be used in reverse as well (emulate a 27C400 in 16-bit mode using a 27C4096).
To use the adapter to read Amiga ROMs or write 27C400 EPROMs select 27c4096 and de-select "check ID" in the Minipro GUI. Then read and write as usual.